Comparative Efficacy of High-Fluoride Toothpaste and Mouth Rinse in Preventing Demineralized Lesions during Orthodontic Treatment
DOI:
https://doi.org/10.65293/jbkcd.v1i01.5Keywords:
Demineralized Lesions, Fluoride Toothpaste, Mouth Rinse, Orthodontics, White Spot Lesions, Risk RatioAbstract
Objective: This study compared the effectiveness of high-fluoride mouth rinse (FMR) and high-fluoride toothpaste (HFT) in preventing demineralized lesions (DLs) during orthodontic treatment.
Study Design: Cross-sectional study
Place and Duration of Study: The study was conducted in the Department of Orthodontics, Khyber College of Dentistry, Peshawar, Khyber Pakhtunkhwa, Pakistan, from June to December 2022.
Methodology: A cross-sectional study was conducted from June to December 2022 at Bacha Khan Medical College, Mardan. A total of 350 orthodontic patients were divided into three groups: Group A (FMR, n=115), Group B (HFT, n=120), and Group C (standard fluoride toothpaste, FT, n=115). Demographic data, oral hygiene habits, fluoride exposure, and DL prevalence were recorded. Risk ratios (RR) and 95% confidence intervals (CIs) were calculated to compare groups.
Results: The prevalence of DLs was significantly lower in Group A (34.8%) and Group B (45.8%) compared to Group C (62.6%) (p<0.001). The mean number of DLs per patient was 1.8 ± 0.9 in Group A, 2.3 ± 1.1 in Group B, and 3.0 ± 1.3 in Group C. Group C had a 1.50 times higher risk of DLs compared to Group A (RR: 1.50, 95% CI: 1.28–1.76). The highest proportion of DLs in the aesthetic zone was in Group C (43.5%).
Conclusion: High-fluoride mouth rinse was more effective in preventing DLs during orthodontic treatment compared to high-fluoride toothpaste and standard fluoride toothpaste.
References
1. Kurniawan FKD, Roestamadji RI, Takahashi N, Tedjosasongko U, Narmada IB, Surboyo MDC, et al. Oral microbiome profiles and inflammation in pregnant women who used orthodontic appliances. Dent J [Internet]. 2022;10(7):118. Available from: http://dx.doi.org/10.3390/dj10070118
2. Benson PE, Parkin N, Millett DT, Dyer F, Vine S, Shah A. Fluorides for the prevention of white spots on teeth during fixed brace treatment. In: Benson PE, editor. Cochrane Database of Systematic Reviews. Chichester, UK: John Wiley & Sons, Ltd; 2004.
3. Dallel I, Ben Salem I, Merghni A, Bellalah W, Neffati F, Tobji S, et al. Influence of orthodontic appliance type on salivary parameters during treatment. Angle Orthod [Internet]. 2020;90(4):532–8. Available from: http://dx.doi.org/10.2319/082919-562.1
4. Flores-Mir C. Do additional high-fluoride interventions among low caries prevalence orthodontic cases using fixed appliances reduce caries incidence? Evid Based Dent [Internet]. 2022;23(3):97. Available from: http://dx.doi.org/10.1038/s41432-022-0803-4
5. Enerbäck H, Lövgren ML, Strömberg N, Westerlund A. Effect of high-fluoride toothpaste and mouth rinse on the prevention of demineralized lesions during orthodontic treatment: a randomized controlled trial. Eur J Orthod [Internet]. 2023;45(5):477–84. Available from: http://dx.doi.org/10.1093/ejo/cjad044
6. Enerbäck H, Lingström P, Möller M, Nylén C, Ödman Bresin C, Östman Ros I, et al. Effect of a mouth rinse and a high-fluoride toothpaste on caries incidence in orthodontic patients: A randomized controlled trial. Am J Orthod Dentofacial Orthop [Internet]. 2022;162(1):6-15.e3. Available from: http://dx.doi.org/10.1016/j.ajodo.2022.03.011
7. Selwitz RH, Ismail AI, Pitts NB. Dental caries. Lancet [Internet]. 2007;369(9555):51–9. Available from: http://dx.doi.org/10.1016/s0140-6736(07)60031-2
8. Hamdan AM, Maxfield BJ, Tüfekçi E, Shroff B, Lindauer SJ. Preventing and treating white-spot lesions associated with orthodontic treatment: a survey of general dentists and orthodontists. J Am Dent Assoc [Internet]. 2012;143(7):777–83. Available from: http://dx.doi.org/10.14219/jada.archive.2012.0267
9. Machado AC, Bezerra SJC, João-Souza SH, Caetano TM, Russo LC, Carvalho TS, et al. Using fluoride mouthrinses before or after toothbrushing: effect on erosive tooth wear. Arch Oral Biol [Internet]. 2019;108(104520):104520. Available from: http://dx.doi.org/10.1016/j.archoralbio.2019.104520
10. Yu J, Qin D, Guo F, Zhao T, He H, Hua F. The effects of preventive interventions for orthodontically induced White Spot lesions: An umbrella review and evidence mapping. J Evid Based Dent Pract [Internet]. 2025;25(2):102089. Available from: http://dx.doi.org/10.1016/j.jebdp.2025.102089
11. Sonesson M, Brechter A, Abdulraheem S, Lindman R, Twetman S. Fluoride varnish for the prevention of white spot lesions during orthodontic treatment with fixed appliances: a randomized controlled trial. Eur J Orthod [Internet]. 2020;42(3):326–30. Available from: http://dx.doi.org/10.1093/ejo/cjz045
12. Cardinal L, da Rosa Zimermann G, Mendes FM, Andrade I Jr, Oliveira DD, Dominguez GC. Dehiscence and buccal bone thickness after rapid maxillary expansion in young patients with unilateral cleft lip and palate. Am J Orthod Dentofacial Orthop [Internet]. 2022;162(1):16–23. Available from: http://dx.doi.org/10.1016/j.ajodo.2021.01.038
13. Kurniawan FKD, Roestamadji RI, Takahashi N, Tedjosasongko U, Narmada IB, Surboyo MDC, et al. Oral microbiome profiles and inflammation in pregnant women who used orthodontic appliances. Dent J [Internet]. 2022;10(7):118. Available from: http://dx.doi.org/10.3390/dj10070118
14. Benson PE, Shah AA, Millett DT, Dyer F, Parkin N, Vine RS. Fluorides, orthodontics and demineralization: a systematic review. J Orthod [Internet]. 2005;32(2):102–14. Available from: http://dx.doi.org/10.1179/146531205225021033
15. Marinho V, Higgins J, Logan S, Sheiham A. Fluoride mouthrinses for preventing dental caries in children and adolescents (Cochrane Review). The Cochrane Library. 2004;(1).
16. Enerbäck H, Möller M, Nylén C, Ödman Bresin C, Östman Ros I, Westerlund A. Effects of orthodontic treatment and different fluoride regimens on numbers of cariogenic bacteria and caries risk: a randomized controlled trial. Eur J Orthod [Internet]. 2019;41(1):59–66. Available from: http://dx.doi.org/10.1093/ejo/cjy025
17. Wang Y, Xu J, Yu C, Zhou X, Chang L, Liu J, et al. Prevention of bacterial biofilm formation on orthodontic brackets by non-crosslinked chitosan coating. Int J Biol Macromol [Internet]. 2023;251(126283):126283. Available from: http://dx.doi.org/10.1016/j.ijbiomac.2023.12628
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Journal of Bacha Khan College of Dentistry

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.







