Comparative Efficacy of High-Fluoride Toothpaste and Mouth Rinse in Preventing Demineralized Lesions during Orthodontic Treatment

Authors

  • Syed Suleman Shah Department of Orthodontics, Khyber College of Dentistry, Peshawar, Khyber Pakhtunkhwa, Pakistan.
  • Muhammad Saood Department of Orthodontics, Khyber College of Dentistry, Peshawar, Khyber Pakhtunkhwa, Pakistan.
  • Palwasha Gul Department of Orthodontics, Khyber College of Dentistry, Peshawar, Khyber Pakhtunkhwa, Pakistan.

DOI:

https://doi.org/10.65293/jbkcd.v1i01.5

Keywords:

Demineralized Lesions, Fluoride Toothpaste, Mouth Rinse, Orthodontics, White Spot Lesions, Risk Ratio

Abstract

Objective: This study compared the effectiveness of high-fluoride mouth rinse (FMR) and high-fluoride toothpaste (HFT) in preventing demineralized lesions (DLs) during orthodontic treatment.

Study Design: Cross-sectional study

Place and Duration of Study: The study was conducted in the Department of Orthodontics, Khyber College of Dentistry, Peshawar, Khyber Pakhtunkhwa, Pakistan, from June to December 2022.

Methodology: A cross-sectional study was conducted from June to December 2022 at Bacha Khan Medical College, Mardan. A total of 350 orthodontic patients were divided into three groups: Group A (FMR, n=115), Group B (HFT, n=120), and Group C (standard fluoride toothpaste, FT, n=115). Demographic data, oral hygiene habits, fluoride exposure, and DL prevalence were recorded. Risk ratios (RR) and 95% confidence intervals (CIs) were calculated to compare groups.

Results: The prevalence of DLs was significantly lower in Group A (34.8%) and Group B (45.8%) compared to Group C (62.6%) (p<0.001). The mean number of DLs per patient was 1.8 ± 0.9 in Group A, 2.3 ± 1.1 in Group B, and 3.0 ± 1.3 in Group C. Group C had a 1.50 times higher risk of DLs compared to Group A (RR: 1.50, 95% CI: 1.28–1.76). The highest proportion of DLs in the aesthetic zone was in Group C (43.5%).

Conclusion: High-fluoride mouth rinse was more effective in preventing DLs during orthodontic treatment compared to high-fluoride toothpaste and standard fluoride toothpaste.

Author Biography

Muhammad Saood, Department of Orthodontics, Khyber College of Dentistry, Peshawar, Khyber Pakhtunkhwa, Pakistan.

Corresponding Author: saudroomi9@gmail.com

References

1. Kurniawan FKD, Roestamadji RI, Takahashi N, Tedjosasongko U, Narmada IB, Surboyo MDC, et al. Oral microbiome profiles and inflammation in pregnant women who used orthodontic appliances. Dent J [Internet]. 2022;10(7):118. Available from: http://dx.doi.org/10.3390/dj10070118

2. Benson PE, Parkin N, Millett DT, Dyer F, Vine S, Shah A. Fluorides for the prevention of white spots on teeth during fixed brace treatment. In: Benson PE, editor. Cochrane Database of Systematic Reviews. Chichester, UK: John Wiley & Sons, Ltd; 2004.

3. Dallel I, Ben Salem I, Merghni A, Bellalah W, Neffati F, Tobji S, et al. Influence of orthodontic appliance type on salivary parameters during treatment. Angle Orthod [Internet]. 2020;90(4):532–8. Available from: http://dx.doi.org/10.2319/082919-562.1

4. Flores-Mir C. Do additional high-fluoride interventions among low caries prevalence orthodontic cases using fixed appliances reduce caries incidence? Evid Based Dent [Internet]. 2022;23(3):97. Available from: http://dx.doi.org/10.1038/s41432-022-0803-4

5. Enerbäck H, Lövgren ML, Strömberg N, Westerlund A. Effect of high-fluoride toothpaste and mouth rinse on the prevention of demineralized lesions during orthodontic treatment: a randomized controlled trial. Eur J Orthod [Internet]. 2023;45(5):477–84. Available from: http://dx.doi.org/10.1093/ejo/cjad044

6. Enerbäck H, Lingström P, Möller M, Nylén C, Ödman Bresin C, Östman Ros I, et al. Effect of a mouth rinse and a high-fluoride toothpaste on caries incidence in orthodontic patients: A randomized controlled trial. Am J Orthod Dentofacial Orthop [Internet]. 2022;162(1):6-15.e3. Available from: http://dx.doi.org/10.1016/j.ajodo.2022.03.011

7. Selwitz RH, Ismail AI, Pitts NB. Dental caries. Lancet [Internet]. 2007;369(9555):51–9. Available from: http://dx.doi.org/10.1016/s0140-6736(07)60031-2

8. Hamdan AM, Maxfield BJ, Tüfekçi E, Shroff B, Lindauer SJ. Preventing and treating white-spot lesions associated with orthodontic treatment: a survey of general dentists and orthodontists. J Am Dent Assoc [Internet]. 2012;143(7):777–83. Available from: http://dx.doi.org/10.14219/jada.archive.2012.0267

9. Machado AC, Bezerra SJC, João-Souza SH, Caetano TM, Russo LC, Carvalho TS, et al. Using fluoride mouthrinses before or after toothbrushing: effect on erosive tooth wear. Arch Oral Biol [Internet]. 2019;108(104520):104520. Available from: http://dx.doi.org/10.1016/j.archoralbio.2019.104520

10. Yu J, Qin D, Guo F, Zhao T, He H, Hua F. The effects of preventive interventions for orthodontically induced White Spot lesions: An umbrella review and evidence mapping. J Evid Based Dent Pract [Internet]. 2025;25(2):102089. Available from: http://dx.doi.org/10.1016/j.jebdp.2025.102089

11. Sonesson M, Brechter A, Abdulraheem S, Lindman R, Twetman S. Fluoride varnish for the prevention of white spot lesions during orthodontic treatment with fixed appliances: a randomized controlled trial. Eur J Orthod [Internet]. 2020;42(3):326–30. Available from: http://dx.doi.org/10.1093/ejo/cjz045

12. Cardinal L, da Rosa Zimermann G, Mendes FM, Andrade I Jr, Oliveira DD, Dominguez GC. Dehiscence and buccal bone thickness after rapid maxillary expansion in young patients with unilateral cleft lip and palate. Am J Orthod Dentofacial Orthop [Internet]. 2022;162(1):16–23. Available from: http://dx.doi.org/10.1016/j.ajodo.2021.01.038

13. Kurniawan FKD, Roestamadji RI, Takahashi N, Tedjosasongko U, Narmada IB, Surboyo MDC, et al. Oral microbiome profiles and inflammation in pregnant women who used orthodontic appliances. Dent J [Internet]. 2022;10(7):118. Available from: http://dx.doi.org/10.3390/dj10070118

14. Benson PE, Shah AA, Millett DT, Dyer F, Parkin N, Vine RS. Fluorides, orthodontics and demineralization: a systematic review. J Orthod [Internet]. 2005;32(2):102–14. Available from: http://dx.doi.org/10.1179/146531205225021033

15. Marinho V, Higgins J, Logan S, Sheiham A. Fluoride mouthrinses for preventing dental caries in children and adolescents (Cochrane Review). The Cochrane Library. 2004;(1).

16. Enerbäck H, Möller M, Nylén C, Ödman Bresin C, Östman Ros I, Westerlund A. Effects of orthodontic treatment and different fluoride regimens on numbers of cariogenic bacteria and caries risk: a randomized controlled trial. Eur J Orthod [Internet]. 2019;41(1):59–66. Available from: http://dx.doi.org/10.1093/ejo/cjy025

17. Wang Y, Xu J, Yu C, Zhou X, Chang L, Liu J, et al. Prevention of bacterial biofilm formation on orthodontic brackets by non-crosslinked chitosan coating. Int J Biol Macromol [Internet]. 2023;251(126283):126283. Available from: http://dx.doi.org/10.1016/j.ijbiomac.2023.12628

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Published

2023-06-30

How to Cite

1.
Shah SS, Saood M, Gul P. Comparative Efficacy of High-Fluoride Toothpaste and Mouth Rinse in Preventing Demineralized Lesions during Orthodontic Treatment. JBKCD [Internet]. 2023 Jun. 30 [cited 2026 Apr. 19];1(01):18-24. Available from: https://jbkcd.bkcd.edu.pk/index.php/website/article/view/5

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